Author contribution
FB and JV: concept and design of study, data acquisition, statistical analysis, and interpretation. Drafting revision and approval of final manuscript to be submitted. CH and BC: concept and design of study, data acquisition, critical revision, and approval of final manuscript to be submitted. SF, RM, ADR, GB, JLL: critical revision and approval of final manuscript to be submitted. VG: validation of methodology. Other authors: critical revision and approval of final manuscript to be submitted.
Technique | Study (year) | Grade | No. of patients | Age (yr)a) | Indication | Procedure | Operative time (min)b) | Complications |
---|---|---|---|---|---|---|---|---|
Hydrosurgery | Gurunluoglu, 2007 [9] | C | 15 | 39.1 | Traumatic (n = 10) | 15.5 | Incomplete graft take (n = 3) | |
Ulcer (n = 2) | 1 (n = 10) | |||||||
Pressure sore (n = 1) | 2 (n = 4) | |||||||
Burn (n = 1) | 3 (n = 1) | |||||||
Infectious (n = 1) | ||||||||
Caputo et al., 2008 [10] | B | 19 | 68 | Ulcer | 1 (n = 21) | 10.8 | No | |
2 (n = 1) | ||||||||
Dillon et al., 2010 [11] | C | 6 | 26.3 | Infectious | 1 | ND | No | |
Vanwijck et al., 2010 [12] | C | 167 | 56 | Ulcer (n = 122) | 1 | ND | Incomplete graft take (n = 8) | |
Pressure sore (n = 28) | ||||||||
Traumatic (n = 13) | ||||||||
Infectious (n = 4) | ||||||||
Fraccalvieri et al., 2011 [13] | B | 27 | 69.4 | Ulcer (n = 16) | 1 | ND | No | |
Infectious (n = 6) | ||||||||
Pressure sore (n = 5) | ||||||||
Liu et al., 2015 [14] | B | 21 | 52.2 | Ulcer (n = 17) | 1 | 14.2 | No | |
Dehiscence (n = 3) | ||||||||
Traumatic (n = 1) | ||||||||
Sivrioglu et al., 2014 [15] | C | 9 | 2.5 | Extravasation injury | 1 | ND | No | |
Ultrasound | Ennis et al., 2005 [16] | A | 55 | ND | Ulcer | 3/wk | 4 | No |
Ennis et al., 2006 [17] | C | 23 | 61.1 | Ulcer | 3/wk | 3–12 | No | |
Kavros et al., 2008 [18] | C | 163 | 70.6 | Ulcer | 3/wk | 3–20 | No | |
Yao et al., 2014 [19] | B | 8 | 58 | Ulcer | 1–3/wk | 5 | No | |
Honaker et al., 2013 [20] | C | 85 | 72 | Pressure sore | 10 | 3–20 | No | |
Jeffers et al., 2014 [21] | C | 4 | ND | Post-surgical | 5–9 | ND | ND | |
Coblation | Richards et al., 2012 [22] | C | 6 | ND | Ulcer (n = 5) | 1 | ND | No |
Pressure sore (n = 1) | 1 | |||||||
Trial et al., 2012 [23] | C | 25 | ND | Burns (n = 15) | 1 | ND | Incomplete graft take (n = 1) | |
Ulcer (n = 4) | ||||||||
Pressure sore (n = 3) | ||||||||
ND (n = 3) |
Technique | Study (year) | Type of studies | Gold standard: scalpel or curette | News therapies | Result |
---|---|---|---|---|---|
Hydrosurgery | Caputo et al., 2008 [10] | Unicentric | 22 | 19 | Significant evidence of a shorter time debridment (10.8 min) using Versajet over conventional debridment (17.7 min) (P < 0.008). |
Prospective | Median time to wound closure 71 day (Versajet) vs. 74 day (conventional) (P = 0.733). | ||||
Randomized | |||||
Liu et al., 2015 [14] | Unicentric | 19 | 21 | No significant difference in terms of cost (P = 0.28). | |
Prospective | No significant difference in time to achieve stable wound closure (P = 0.77). | ||||
Randomized | No difference in quantitative bacterial counts (P = 0.376). | ||||
Ultrasound | Ennis et al., 2005 [16] | Multicentric | 28 | 27 | Significant reduction in the exudation at wk 5 (P = 0.001). |
Prospective | Mean time to healing shorther in group using ultrasound therapy (9.12 wk) compare to control (11 wk) (P = 0.0366). | ||||
Randomized | Proportion of wounds healed at wk 12 is higher in ultrasound group (40.7%) compared to group (14.3%) (P = 0.0366). | ||||
Kavros et al., 2008 [18] | Unicentric | 47 | 163 | A significant rates of healing in ischemic (P = 0.049), neuropathy (P = 0.08) and venous (P = 0.02) wounds. | |
Retrospective | |||||
Non randomized | |||||
Yao et al., 2014 [19] | Unicentric | 4 | 8 | No statistically significant difference. | |
Prospective | |||||
Randomized | |||||
Honaker et al., 2013 [20] | Unicentric | 63 | 43 | Significant decrease in wound severity between groups for the discharge assessment (P < 0.005). | |
Retrospective | |||||
Non randomized |